Oxidative stress
What it is
Oxidative stress describes a state in which reactive chemistry exceeds the capacity of protective and repair systems.
What it does
It can contribute to damage to cellular components.
Research context and ingredient forms
Reactive molecules also have normal biological functions, so eliminating all such activity is not a useful goal.
Using this information
A lower laboratory marker should not automatically be presented as disease prevention. Identify the marker, intervention, and demonstrated clinical outcome.
Scientific Research & References
- NCI Dictionary of Cancer Terms: oxidative stress
National Cancer Institute
Limitations: Terminology support only; not evidence of benefit for a particular intervention.
Source assessment recorded.
- Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo
Michael P. Murphy, Hülya Bayir, Vsevolod Belousov, Christopher J. Chang, Kelvin J. A. Davies, Michael J. Davies, Tobias P. Dick, Toren Finkel, Henry J. Forman, Yvonne Janssen-Heininger, David Gems, Valerian E. Kagan, Balaraman Kalyanaraman, Nils-Göran Larsson, Ginger L. Milne, Thomas Nyström, Henrik E. Poulsen, Rafael Radi, Holly Van Remmen, Paul T. Schumacker, Paul J. Thornalley, Shinya Toyokuni, Christine C. Winterbourn, Huiyong Yin, Barry Halliwell
2022 · Nature Metabolism · Original expert consensus statement on measurement methods
Limitations: Methods and terminology guidance. Does not establish a food or supplement treatment benefit.
Source assessment recorded.
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